The 17 best anti-aging hand creams of 2025, according to dermatologists

Size: 3 ounces | Scented: No | Hero ingredients: Hyaluronic acid, niacinamide, ceramides | Form: Lotion | Skin Type: For dry skin

Two of the dermatologists we talked with raved about this CeraVe hand cream, and thousands of Amazon shoppers are fans, too. Jaliman recommends it because "it contains hyaluronic acid which hydrates the skin, and ceramides which help to protect the skin barrier. And it has niacinamide, which evens skin tone." Dr. Sonia Batra, host of the CBS syndicated daytime talk show The Doctors and a board-certified dermatologist, likes it too: "It absorbs quickly and can be used throughout the day after handwashing without feeling greasy. It contains three ceramides to restore the barrier of the skin and is fragrance free." Bonus: It’s super affordable.

Size: 1.69 ounces | Scented: Yes | Hero ingredients: Lanolin, vitamin E | Form: Lotion | Skin Type: For dry skin

This rose-scented hand cream is a top pick of Zeichner’s. "This ultra-rich moisturizer does a great job of hydrating and protecting the skin without leaving my hands feeling heavy or greasy," he said. "Its hero ingredient is lanolin, the same ingredient that makes sheep’s wool waterproof. Plus, it contains a rose extract with known antioxidant benefits, which is why it is commonly used in anti-aging skin care products." He’s not the only one who is a fan. Hundreds of shoppers love it too, with one buyer calling it the "best hand cream EVER!"

Size: 13 ounces (pack of 3) | Scented: No | Hero ingredients: Petroleum jelly | Form: Gel | Skin type: For all skin types

While it’s not technically a hand cream, that doesn't bother experts. Both Dr. Purvisha Patel, a board-certified dermatologist and founder of Visha Skincare, and Dr. ​Mona Gohara, a board-certified dermatologist and associate clinical professor of dermatology at Yale School of Medicine, recommended using Vaseline to keep your hands looking youthful. "It’s made from a purified mineral oil that is the ultimate barrier repair cream, making it great for nights and cold days," Gohara said. Along with protecting and hydrating skin, the noncomedogenic formula also helps reduce the appearance of fine lines for a more youthful appearance.

Size: 2.5 ounces | Scented: No | Hero ingredients: Retinol, squalene, shea butter, glycerin | Form: Lotion | Skin type: For all skin types

Thanks to its ability to reduce wrinkles and even out skin tone, retinol is one of the most powerful anti-aging treatments out there — so it makes sense that it’s the main ingredient in this dermatologist-approved hand cream. Jaliman likes it because "it also contains squalene, shea butter and glycerin, which are extremely hydrating. It is also fragrance-free." It’s definitely pricey, but shoppers say it’s well worth the cost. "I normally would not pay as much for a hand cream, but in this case, I am on my second tube. My hands have not looked this good in years. The spots are barely visible. I am usually skeptical about product descriptions, but this one is right on," raved one. Moisturizing and reduces the appearance of age spots? Yes, please!

Size: 1.7 ounces | Scented: No | Hero ingredients: Vitamin E, macadamia nut oil, retinol | Form: Lotion | Skin type: For all skin types

This multitasker not only helps fight wrinkles on your face, but Zeichner says it also works great on your hands. "It combines Coenzyme Q10, which is a potent antioxidant with a retinyl ester to strengthen and smooth the skin. Since it is not irritating, it can be used across all skin types, even in people who are sensitive," he added. Along with being fragrance-, alcohol- and dye-free, the cream is packed with other hydrating and anti-aging ingredients, including vitamin E, macadamia nut oil and retinol to smooth and strengthen skin.

Size: 15 ounces | Scented: Yes | Hero ingredients: Retinol, ferulic acid, vitamin E, shea butter, green tea extract, chamomile, aloe vera | Form: Lotion | Skin type: For all skin types

While this powerful antioxidant-rich formula by Medix 5.5 can be used anywhere on your body, people say it works wonders on their hands. Nearly 19,000 Amazon shoppers have given the fast-acting formula their seal of approval because it helps minimize the appearance of wrinkles and age spots caused by sun exposure and improves skin tone and elasticity — and it smells amazing to boot. One verified customer said, "I bought this for my mama because her hands were starting to get that crepe-like texture. Her hands are much better and it helped lighten the dark spots, too."

Size: 1 ounce | Scented: No | Hero ingredients: Vitamin C, peptides | Form: Serum | Skin type: For all skin types

Although it’s marketed for the face, this vitamin C-packed serum by RoC is one of Zeichner’s top picks for hands. "This serum contains a stabilized form of vitamin C, which is known to brighten dark spots and even skin tone, while offering protection against free radical damage that the hands are exposed to on a daily basis," he said. While it will aim to reduce the appearance of age spots and hyperpigmentation from sun exposure, it isn’t as hydrating as most options since it’s not a cream, so we recommend layering on a regular hand lotion, too.

Size: 1 ounce | Scented: No | Hero ingredients: Sea buckthorn fruit extract, meadowfoam seed oil, argan oil | Form: Lotion | Skin type: For dry skin

Since pesky UV rays are among the biggest causes of early aging, investing in a good hand cream with a high SPF is the best way to avoid future damage like age spots. This option from Supergoop! not only has SPF 40 for optimal sun exposure protection, but it’s also infused with powerful antioxidants and natural oils to nourish, moisturize and brighten the skin on your hands. I’ve kept a bottle in my car ever since my dermatologist told me how damaging the sun can be, even through car windows, and I love to put it on every time I head out for a long ride.

Size: 2.5 ounces | Scented: Yes | Hero ingredients: Mandarin rind, rosemary leaf, cedar atlas | Form: Lotion | Skin type: For all skin types

If you’re picky about textures in hand creams like Deals Writer Taylor Lane, you’re in luck. She has found an option with the "dreamiest consistency." Lane adds that "it blends in immediately and doesn't leave a greasy finish behind. It instantly hydrates hands and smooths cuticles. I also love its gentle ingredients like rosemary and mandarin rind. And the scent is gorgeous!" Nearly 1,400 Amazon shoppers are also fans, with one raving, "You need only use a small dab on the back of each hand and then work it in. I do this at night before bed and put gloves on to sleep in. My skin feels so much better. I recommend this balm to anyone needing help keeping or obtaining youthful hands."

Size: 2 ounces | Scented: No | Hero ingredients: Hyaluronic acid, plantain leaf extract, peptides | Form: Lotion | Skin type: For dry skin

This super-hydrating hand cream by StriVectin is a popular option and rightfully so — it’s specially formulated with plantain leaf extract that works to firm loose, crepey skin and reduce the appearance of age spots. Jaliman is a fan because it also boasts "peptides that stimulate collagen production and shea butter and glycerin for hydration." Bonus: You don’t need to use a lot to see results. One happy Amazon customer wrote, "This is by far the best hand cream that I have ever used! StriVectin products are the best! After only three days of using this hand cream, my hands are showing a big difference! Less crepey skin and more volume! You don't need to apply a lot, a little goes a long way! Will be ordering again!"

Size: 2.2 ounces | Scented: No | Hero ingredients: Marula oil, niacinamide, peptides | Form: Lotion | Skin type: For all skin types

Sleek packaging, cruelty-free ingredients, hypoallergenic and powerful? It’s no wonder Katelyn Mullen, our commerce managing editor, adores this fragrance-free hand cream. "I’ve tried quite a few brands across many price points to help my hands look more hydrated and less ... old," she said. "I found all my previous creams to be too oily, until I tried Nécessaire’s the Hand Cream. The texture is soft, there is no scent and it absorbs quickly, which was my No. 1 requirement. The only downside is the price. I use it often so I have been going through it a little faster than I’d like at this price point." This hand cream was awarded the Seal of Approval by the National Eczema Association, making it perfect for anyone with the skin condition.