Rocket sirens have sounded in southern and central Israel as Palestinian militants in Gaza responded to Israeli air strikes which killed at least 10 people, including a senior commander of the Palestinian Islamic Jihad movement.
As darkness fell, Israeli authorities said sirens had been sounded in southern and central areas, while images broadcast by Israeli television stations appeared to show a number of missiles being shot down by air defence systems.
In Tel Aviv, Israel's economic centre, witnesses said they could hear booms but there were no reports of sirens.
Islamic Jihad said it had fired more than 100 rockets on Friday into Israeli cities, including Tel Aviv.
Israel's ambulance service said there were no reports of casualties.
Earlier, local health officials in Gaza said at least 10 people, including a five-year old child, had been killed and 55 wounded in the Israeli airstrikes, which came after days of escalating tensions following the arrest of a Palestinian militant leader during the week.
An Israeli spokesperson said the strikes had killed Islamic Jihad commander Tayseer al-Jaabari and about 15 "terrorists" but said the military did not have a final casualty total.
"Israel carried out a precise counterterror operation against an immediate threat," Israeli Prime Minister Yair Lapid said in a televised statement in which he pledged to do "whatever it takes to defend our people".
"Our fight is not with the people of Gaza. Islamic Jihad is an Iranian proxy that wants to destroy the state of Israel and kill innocent Israelis," he said.
An Islamic Jihad official confirmed that al-Jaabari, whom the Israeli military described as the main co-ordinator between Islamic Jihad and Hamas, had been killed in the strikes, which hit several targets around the densely populated strip.
Smoke rose from a building where al-Jaabari was apparently killed and glass and rubble were strewn across the street amid the sound of ambulances racing to other sites.
As mourners prepared to hold funerals for those killed in the attacks, hundreds of people, some holding Palestinian flags, marched through the streets of Gaza.
The strikes came after Israel arrested Bassam al-Saadi, a senior leader of the Islamic Jihad group, during a raid in the occupied West Bank city of Jenin earlier this week.
It subsequently closed off all Gaza crossings and some nearby roads over fears of retaliatory attacks from the group, which has a stronghold in Gaza, further restricting Palestinian movement.
Israel's military said Defence Minister Benny Gantz had approved plans to call up 25,000 reservists following the strikes, signalling that Israel expected an extended confrontation.
In an interview on Al Mayadeen television, a pro-Iranian Lebanese channel, Islamic Jihad leader Ziad al-Nakhala vowed retaliation for the strikes.
"There are no red lines in this battle and Tel Aviv will fall under the rockets of resistance, as well as all Israeli cities," he said.
Hamas' armed wing issued a statement saying: "The blood of our people and our mujahideen will not go in vain."
Islamic Jihad, one of a cluster of Palestinian militant groups, was founded in Gaza in the 1980s and opposes political dialogue with Israel.
Considered close to Iran, it is separate from Hamas but generally co-operates closely with the movement.
The Israeli military spokesperson said authorities expected there would be rocket attacks against the centre of Israel but said Iron Dome anti-missile batteries were operational.
He said special measures had been imposed in Israeli areas 80 kilometres around Gaza.
He said plans to allow fuel trucks into Gaza to keep the area's sole power plant operational had been dropped at the last minute as intelligence picked up movements that indicated attacks on Israeli targets were imminent.
The lack of fuel is set to lead to more power cuts in Gaza, where residents already have just 10 hours of electricity a day, and further hit the economy of a region that depends on foreign aid and still struggles to recover from past wars.
A narrow strip of land where 2.3 million people live on a patch of 365 square kilometres, Gaza has been a constant point of conflict ever since Hamas took control.
The area has since been under blockade, with Israel and Egypt tightly restricting movement of people and goods in and out.
"We have not yet been able to reconstruct what Israel had destroyed a year ago. People didn't have the chance to breathe, and here Israel is attacking again without any reason," said Mansour Mohammad-Ahmed, 43, a farmer from central Gaza.
Friday's attack came as Egyptian officials had been seeking to mediate between Israel and Hamas, and an Islamic Jihad statement said the strikes appeared aimed at undermining mediation efforts.
Israel has fought five conflicts with Gaza since 2009, the most recent an 11-day war in May 2021 when Hamas fired thousands of rockets into Israel killing 13 people and Israel pounded the strip with airstrikes that killed at least 250 Palestinians.