Jessica Capshaw and Camilla Luddington on worst 'Grey's Anatomy' guest star: 'Yelled at everyone'

The BFFs and "Call It What It Is" podcast hosts want you to join their "friendship circle" — and they aren't afraid to dish.

Jessica Capshaw and Camilla Luddington stand close as they pose for the camera.
Jessica Capshaw and Camilla Luddington talk about their new podcast and reflect on their time on Grey's Anatomy. (Corbis via Getty Images)

Call it what it is ... some actors can just be the worst.

Grey's Anatomy stars Jessica Capshaw and Camilla Luddington, co-hosts of iHeartRadio's Call It What It Is podcast, get to handpick the guests that come on their show so they don't have rude encounters. (Unless they want them ... more on that later.) But they can't say the same for their time at Grey Sloan Memorial Hospital.

"There's a definite name that pops in my head," Capshaw told Yahoo Entertainment when asked about the worst guest star during her time on the medical drama. (Capshaw, who played Dr. Arizona Robbins, left at the end of Season 14 in 2018.)

"Yeah," Luddington agreed, but said the person she was thinking of was different. "You know what's funny though, [Jessica] knows what my name is. I actually don't necessarily know what your name [is], but it cannot be the same person."

"It's not," Luddington went on to confirm. When asked what the unnamed actor did that was so bad, Capshaw interjected: "Yelled at everyone."

"That never goes down well," said Luddington, who is on her 13th season of playing Dr. Josephine "Jo" Wilson on the long-running ABC series.

"Screamed," added Capshaw.

For redditors trying to figure out who the person might be, the only hint the pair gave is as follows.

"You know what I'll say is that the episode that they were in just happened to not ever air," Luddington revealed. "Not because of [their behavior], because circumstances that happened and story change."

Luddington and Capshaw speak to each other in the hospital in a scene from Grey's Anatomy.
Luddington and Capshaw share a scene in Grey's Anatomy. (Anne Marie Fox/Disney)

Two suspects to promptly rule out: Geena Davis, who Capshaw said was her favorite guest star, and Beanie Feldstein.

"Beanie was my favorite," Luddington said. "I'd never met her before and she was coming off of some huge movies. And you never know what someone's gonna be like. And she was so gracious and so excited and just warm and delicious that I would've wanted her to stay forever."

"We usually had such incredible guest stars," Capshaw said. "And being a guest star is very intimidating when you come on. Most people certainly know of the show, or they're actual fans of the show. So when they come in, they come in so soft and open and kind and ready to work. And I think that when I was there, I remember it was always a No. 1 priority to make sure that guest stars felt at home."

The ladies may not be interested in having a screamer on their podcast, but being "grumpy" isn't a deal-breaker. When asked who they'd like to sit down with most, Capshaw said she's been drawn to Hugh Grant lately.

"For some reason I keep seeing these snippets of Hugh Grant being grumpy that have made me laugh so hard," she explained.

"I did a chemistry test with him," Luddington revealed, which was news to her BFF.

"For what?!" Capshaw asked.

"It was [a] comedy back in the day and I was in the room with him and it was very funny and I didn't get it," Luddington recalled.

"Was he grumpy?" Capshaw asked.

"He's always grumpy!" Luddington said.

"I wanna have him on to talk about his grump," Capshaw confirmed.

Luddington and Capshaw's funny banter is a staple of their podcast, and they hope to "build community" and promote "belonging" with each episode, whether it's talking about mental health or Taylor Swift.

"We want us to all feel like our friendship circle is here. We can talk about anything, you can tell each other anything. There's no judgment, but we're all in it together," Luddington said, explaining that they want to present "a sense of feeling like there's someone else out there that is going through the same thing that you are."

She continued, "We talk about the loneliness epidemic offline. We talk about wanting to solve for that and creating a space where people can jump in, you know, whatever episode they're listening to and feel like they're just joining their friends and listening along, and that their friends are gonna be honest and they're gonna be kind."

"Call it what you will, but I believe deeply in joy being an antidote to most things," Capshaw agreed. "I believe that gratitude is also an antidote. I also believe that in the darkest of days, the thing that will get you out is hoping for something better. So I think if you put all those together and you think about what we've set out to do, what we've set out to do is check all those boxes while we have a good time."

"I hope you laugh with us," Luddington added. "Sometimes we're talking about serious things that are painful and we gotta laugh. So I just hope that if there's someone out there listening and they're hurting in some way, if we manage to have them laugh along with us, then [we've] done it."

New episodes of Call It What It Is drop Wednesdays and Sundays.