Child serial killer Lucy Letby has been refused permission to appeal against her convictions.
The nurse from Hereford was convicted in August of the murders of seven babies and the attempted murders of six others.
She killed her victims by injecting them with insulin or air, or force feeding them milk.
The 33-year-old was sentenced to 14 whole life orders, meaning she joined the country's most notorious killers and can never be released.
Letby pleaded not guilty and maintained her innocence throughout the trial.
She first sought permission to appeal against her convictions in September.
However, a Court of Appeal judge refused her application after looking at case documents, a spokesman confirmed on Tuesday.
Such applications are usually considered by a single judge without a hearing.
If rejected, the person has two weeks to reapply at a full court hearing in front of two or three judges.
Letby killed the babies at the neonatal unit of Countess of Chester Hospital between 2015 and 2016.
Jurors at her trial at Manchester Crown Court were unable to reach verdicts on six attempted murder charges relating to five babies.
She will be retried at the same court in June on a single count that she tried to murder a girl, Child K, in February 2016.